Multimeric arrays of the yeast retrotransposon Ty.
نویسندگان
چکیده
منابع مشابه
Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.
The target site distribution for 55 independent Ty insertions that inactivate the function of the Saccharomyces cerevisiae CAN1 gene is reported. Under some selection conditions Ty elements inserted preferentially into the promoter and exhibited an orientation bias. In contrast, under other conditions no insertions were detected in the promoter region and transposition appeared to occur randoml...
متن کاملExpression strategies of the yeast retrotransposon Ty: a short sequence directs ribosomal frameshifting.
The Ty element of yeast is a member of a class of eukaryotic transposons which bear a striking resemblance to retroviral proviruses in their structure and expression strategies (1,2). A direct comparison can be drawn between the production of a fusion protein encoded by Ty, resulting from a frameshift event which fuses two out-of-phase open reading frames TYA and TYB, and the production of Pr18...
متن کاملCryo-electron microscopy structure of yeast Ty retrotransposon virus-like particles.
The virus-like particles (VLPs) produced by the yeast retrotransposon Ty1 are functionally related to retroviral cores. These particles are unusual in that they have variable radif. A paired mass-radius analysis of VLPs by scanning transmission electron microscopy showed that many of these particles form an icosahedral T-number series. Three-dimensional reconstruction to 38-A resolution from cr...
متن کاملTy Elements of the Yeast Saccharomyces Cerevisiae
Transposable elements in the yeast Saccharomyces cerevisiae are a heterogeneous group of mobile genetic elements. Ty elements transpose via an intermediate RNA-molecule using the same replication and integration mechanisms as the metazoan retroviruses. Ty1 is a retrotransposons with life cycle very similar to that of oncogenes. This similarity provides an attractive model for virus-host interac...
متن کاملTranscriptional induction of Ty recombination in yeast.
Families of repeated sequences are present in the genomes of all eukaryotes. Little is known about the mechanism(s) that prevents recombination between repeated sequences. In the yeast Saccharomyces cerevisiae, recombination between homologous sequences placed at nonhomologous locations in the genome (ectopic recombination) has been shown to occur at high frequencies for artificially created re...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1990
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.10.6.2882